Job Information
Children's Hospital Boston Research Assistant II in Boston, Massachusetts
79001BRJob Posting Title:Research Assistant IIDepartment:Pediatrics-Hematology/Oncology AutoReqId:79001BRStatus:Full-TimeStandard Hours per Week:40 Job Posting Category:ResearchJob Posting Description: Dr. Gerdemann's research lab is a young, dynamic and innovative laboratory embedded within the larger CTSI research community at Boston Children’s Hospital, focusing on the mechanisms of cancer-directed T cell therapeutics, including chimeric antigen receptor (CAR) engineered T cells.
Our research employs a diverse range of in vivo and in vitro models, including state-of-the-art non-human primate models of transplantation and CAR T cell therapy, patient-derived samples, and xenogeneic human-to-mouse cancer models to perform detailed mechanistic studies. This work has led to the identification of novel immune pathologies in CAR T cell therapy. Position Overview We are seeking a highly motivated candidate to join our cellular therapy research team to advance CAR T cell therapeutics with the goal of translating key findings into clinical applications for pediatric oncology . The candidate will work with non-human primate and human cells, as well as xenogeneic models , generating impactful data to improve CAR T cell therapies.
In addition to research responsibilities, the candidate will also serve as the lab manager , overseeing lab organization, inventory management, and ordering supplies , ensuring efficient daily operations. This role provides an excellent opportunity to develop higher-level management and organizational skills while contributing to innovative CAR T cell research.
Key Qualifications
The ideal candidate should have:
✔ Strong organizational skills, attention to detail, and a solid work ethic
✔ Ability to quickly learn new techniques and work collaboratively in a team-oriented environment
✔ Bachelor’s degree (or near completion) in biology, biochemistry, chemistry, or a related field
✔ Research Assistant II applicants should have at least one year of relevant research experience
Preferred Experience:
Background in immunology, molecular biology, biochemistry, or cell biology
Experience in sample processing, flow cytometry, cell sorting, or molecular biology techniques
Knowledge of CRISPR/Cas9-based gene editing
Familiarity with lab safety protocols and handling of hazardous materials
Experience working with animal/mouse models is a plus
Strong problem-solving skills and adaptability to work flexible hours as needed
Key Responsibilities
Process blood and tissue biopsy samples from human and non-human primates
Perform multicolor flow cytometry and cell sorting
Conduct in vitro T cell immune assays and CAR T cell generation/evaluation
Perform cloning, molecular biology, and CRISPR/Cas9 gene editing techniques
Construct bulk and single-cell cDNA libraries for Next-Gen sequencing
Lab management duties, including inventory control, reagent supply maintenance, and ordering
Why Join Us?
This position offers an opportunity to work in a high-impact, collaborative, and engaging research environment, where you will gain hands-on training in cutting-edge immunological techniques. You will be part of a team dedicated to making a direct impact on pediatric cancer treatment through innovative CAR T cell research.
Compensation and job title will be commensurate with the candidate’s qualifications and experience.
Office/Site Location:BostonRegular, Temporary, Per Diem:Regular Remote Eligibility :Onsite Only