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Dana-Farber Cancer Institute Research Fellow - Pediatric Oncology/Crompton Lab in Boston, Massachusetts

Located in Boston and the surrounding communities, Dana-Farber Cancer Institute brings together world renowned clinicians, innovative researchers and dedicated professionals, allies in the common mission of conquering cancer, HIV/AIDS and related diseases. Combining extremely talented people with the best technologies in a genuinely positive environment, we provide compassionate and comprehensive care to patients of all ages; we conduct research that advances treatment; we educate tomorrow's physician/researchers; we reach out to underserved members of our community; and we work with amazing partners, including other Harvard Medical School-affiliated hospitals.

A full-time post-doctoral fellow position is available in the laboratory of Dr. Brian Crompton in the Department of Pediatric Oncology at the Dana-Farber Cancer Institute for a highly motivated individual. The Crompton laboratory is recruiting a fellow to focus on genomic profiling and analyses of human tissue samples and disease models to understand mechanisms of cancer heterogeneity and evolution in pediatric sarcomas. The laboratory uses a combination of next-generation sequencing approaches to profile tumor material from matched tumor biopsies, circulating tumor DNA, and circulating tumor cells. Profiling is performed as “bulk” sequencing experiments and as single-cell analyses to give us a complete picture of genomic and epigenomic heterogeneity and disease evolution. Validation of novel findings will utilize relevant cell line and animal models of cancer.

Ideal candidates would have experience and a desire to learn to handle human tissue samples, perform bioinformatic analyses of genomic data, and validate findings at the bench. The laboratory is situated in an ideal academic setting with unparalleled access to collaborators throughout the Harvard Medical School system and affiliated hospitals. Dr. Crompton has an academic appointment at the Broad Institute and research projects regularly involve collaborations with other Broad investigators. Our proximity to a major hub of medical industry also creates opportunities for collaborations with industry leaders in cancer therapeutics and clinical cancer genomics. Mentorship of the candidate will focus on the development and publication of high-impact research projects and preparing the fellow for a career as an independent academic investigator or for a position in the biomedical industry.

PhD, MD, or MD/PhD

Mastery of laboratory bench techniques

Experience with computational analyses

Willingness to learn and master new laboratory and computation techniques

Excellent written and oral communication skills

Strong organizational skills, including the ability to handle a variety of tasks in a fast-paced environment

We are looking for candidates who have at least two years of availability.

Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other groups as protected by law.

Job ID: 2017-6265

Grade: 41

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